

You can normally add it to steam to see if proton will work, or if not, you could use heroic, lutris, or bottles, although normally if it doesnt work under proton and there isn’t a premade wine prefix in lutris or heroic, it will take some tinkering.
Which games are you worried about?
Itch is a bit spotty if you don’t want to configure your prefix and it doesn’t work under proton, but pirated games work fairly well in lutris using the official versions prefix